資料參考來源

*β-乳球蛋白 ​

1. a. 關鍵致敏蛋白：指完整的β-乳球蛋白。β-乳球蛋白是牛乳中的主要過敏原，約有82%的牛乳過敏患者對β-乳球蛋白過敏。. He. SF. et al. Journal of Food Safety and Quality Apr. , 2019 b. 近乎0發現：指近似於零。特定的檢測結果顯示， Aptamil ESSENSIS PHP親熠4配方的β-乳球蛋白未檢出。（實驗室資料）​

2. 根據一項多國、隨機、雙盲、對照臨床研究，使用含scGOS/lcFOS和短雙歧桿菌M-16V的配方奶餵養50名寶寶約22周，發生皮膚疾病的寶寶比例和對照組相比下降了約52%。Chua M C，et al. Journal of Pediatric Gastroenterology and Nutrition, 2017, 65(1):102. 約52%為試驗資料，供消費者參考，具體效果因人而異。​

3. 精鑽切割指精準切割致敏牛奶蛋白，精准保留小分子乳蛋白，為寶寶提供營養支援。精“鑽”用以形容切割蛋白的珍稀和精準。​

4. 乳清蛋白的分子大小為納米水準。de Wit, Nutritional and Functional Characteristics of Whey Proteins in Food Products. J Dairy Sci.1998; 81: 597-608.​

5. 紐迪希亞在蛋白質水解領域有超過40年的研發歷史。​

6. 在Aptamil部分水解配方乳清蛋白水解產物中觀察到關鍵致敏蛋白β-乳球蛋白的完全水解。van Esch, Betty C A M et al. “In vivo and in vitro evaluation of the residual allergenicity of partially hydrolysed infant formulas.” Toxicology letters vol. 201,3 (2011): 264-9.​

7. 中華醫學會兒科學分會消化學組, 等. 嬰幼兒功能性消化不良綜合征非藥物干預專家共識（2024）[J]. 中華兒科雜誌. 2024;62(6):514-519.​

8. EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA) et al. “Nutritional safety and suitability of a specific protein hydrolysate derived from whey protein concentrate and used in an infant and follow-on formula manufactured from hydrolysed protein by Danone Trading ELN B.V.” EFSA journal. European Food Safety Authority vol. 18,11 e06304. 28 Nov. 2020.​

9. 何聖發,陳紅兵,龍彩雲,等.牛乳過敏原β-乳球蛋白檢測方法的研究進展[J].食品安全品質檢測學報,2019,10(07):1763-1769.​

10. SYNEO，是指M-16V與GOS/FOS的組合​

11. 母源自護菌種：指短雙歧桿菌，是能從媽媽產道被廣泛發現的菌種，“自護”指短雙歧桿菌能抑制雜菌，自己保護自己順利定植。a. Bozzi Cionci N, et al. Therapeutic Microbiology: The Role of Bifidobacterium breve as Food Supplement for the Prevention/Treatment of PaediatricDiseases. Nutrients. 2018 Nov 10;10(11):1723. b. E.M.M. Quigley, Chapter 15 - Bifidobacterium breve, Editor(s): Martin H. Floch, Yehuda Ringel, W. Allan Walker,TheMicrobiota in Gastrointestinal Pathophysiology, Academic Press, 2017, Pages 135-137, ISBN 9780128040249, https://doi.org/10.1016/B978-0-12-804024-9.00015-X. ​

12. 自護益生元是組成SYNEO的“關鍵成分”。“自護益生元”指短鏈低聚半乳糖scGOS和長鏈低聚果糖lcFOS的益生元組合。 Salminen S, et al. Infant Formula Supplemented with Biotics: Current Knowledge and Future Perspectives[J]. Nutrients, 2020. ​

13. 成分研究: Arslanoglu S. et al. J Biol Regul Homeost Agents. 2012 Jul-Sep;26(3 Suppl):49-59. , Wang Y et al. Eur J Clin Nutr. 2025 Feb 6.​

14. 比較物件為不含SYNEO組的嬰幼兒配方奶粉的寶寶。SYNEO組能使好菌更快定植，提高雙歧桿菌數量。 Chua MC, et al. Effect of Synbiotic on the Gut Microbiota of Cesarean Delivered Infants: A Randomized, Double-blind, Multicenter Study. J Pediatr Gastroenterol Nutr. 2017 Jul;65(1):102-106.​

15. Scholtens PA, Alliet P, Raes M, et al. Fecal secretory immunoglobulin A is increased in healthy infants who receive a formula with short-chain galacto-oligosaccharides and long-chain fructo-oligosaccharides. J Nutr (2008); 138(6): 1141-1147.​

16. 5HMO (0.7g克/100g克): 2’-FL, LNT, 3-FL, 6’-SL, 3’-SL.​

17. 結合scGOS/lcFOS (5.3g/100g)，低聚糖含量達9.1g/L，與母乳水平相約。​